F22: A Meissner's corpuscle. Seen bracketed, these are found unevenly distributed in the CT of the dermal papillae (*) of the integument. This slide is from thick skin. These structures function in mediating light touch and tactile feeling. The arrow shows the dendritic nerve fiber which spirals into a spindle-shaped structure in contact with the epidermis. The entire structure is ensheathed by a connective tissue capsule.